Des Peres
Des Peres
San Antonio
San Antonio
Flight Driving

Des Peres to San Antonio

Updated: 31 May 2026

The journey from Des Peres to San Antonio is approximately 1,400 km. You can drive via I-44 W and I-35 S, which takes about 14 hours. Alternatively, you can fly from St. Louis Lambert International Airport to San Antonio International Airport.

Total Distance: 1,400 km driving distance; 1,200 km straight-line air distance.
Fastest Way
Flying takes 3 hours.
Cheapest Way
Driving is the most economical for groups.
Compare Des Peres to San Antonio Routes
Flight
Direct
Driving
Direct
Duration 3 hours 14 hours
Avg Price $250 - $500 $180 - $300
Operator Southwest Airlines Personal Vehicle
Route STL to SAT. I-44 W to I-35 S.
Tip Fastest way to travel. Long drive, plan for stops.
Travel Tips
  • Traffic
    Avoid San Antonio rush hour.
  • Parking
    Use secure parking garages.
  • Events
    Check for local events.
  • Dining
    Try Tex-Mex cuisine.
  • Navigation
    Use GPS for city navigation.
Safety Tips
  • Driving
    Stay alert on the highway.
  • Weather
    Check for weather alerts.
  • Vehicle
    Check your car before the trip.
  • Emergency
    Keep a roadside kit.
People Also Ask
  • How long is the drive?
    It takes about 14 hours.
  • Is there a train?
    No, there is no direct rail service.
  • Are there tolls?
    Yes, expect tolls in Texas.
  • What is the best way?
    Flying is the most convenient.
  • Is it safe?
    Yes, it is a standard drive.
Quick Info
  • From Des Peres, Missouri, United States
  • To San Antonio, Texas, United States
  • Modes
Best Time to Travel

Spring and Fall for mild weather.

Things to Do in San Antonio
1
The Alamo
Visit the historic mission.
2
River Walk
Enjoy the scenic river walk.
3
San Antonio Missions
Explore the historic missions.
4
Tower of the Americas
See panoramic views of the city.
Tags
Des Peres to San Antonio driving to San Antonio flight to San Antonio Missouri to Texas San Antonio travel guide road trip to San Antonio St Louis to San Antonio best way to San Antonio