Driving
Myrtle Beach to Florence
Updated: 28 May 2026
The trip from Myrtle Beach to Florence is a 110-kilometer journey. Driving via US-76 takes about 1.5 hours. There are no direct flights between these cities. Florence is a major hub in the Pee Dee region of South Carolina.
Total Distance: 110 km driving, 100 km air distance.
Fastest Way
Driving is the fastest method.
Cheapest Way
Driving is the only practical and cheapest way.
Compare Myrtle Beach to Florence Routes
Driving
Direct
Duration
1 hour 30 mins
Avg Price
15-25 dollars in fuel
Operator
Personal Vehicle
Route
US-76 W.
Expect a straightforward drive.
Travel Tips
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WalkingDowntown is very walkable.
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FoodTry the local Southern cuisine.
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HistoryVisit the historic sites in the city.
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ParkingParking is available in the city.
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NatureEnjoy the local parks.
Safety Tips
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General SafetyStay in well-lit areas at night.
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Public TransitKeep your belongings secure.
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DrivingBe prepared for local traffic.
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EmergencyDial 911 for any emergency.
People Also Ask
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How long is the drive?It takes about 1.5 hours.
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Are there direct flights?No, there are no direct flights.
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Is Florence walkable?Yes, the downtown area is pedestrian-friendly.
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What is the best time to visit?Spring and fall are ideal.
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Are there tolls?No, this route is toll-free.
Quick Info
- From Myrtle Beach, South Carolina, United States
- To Florence, South Carolina, United States
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Modes
Best Time to Travel
Spring and Fall for pleasant weather.
Things to Do in Florence
1
Florence County Museum
Explore the local history and art.
2
Timrod Park
Enjoy the beautiful park.
3
Downtown Florence
Enjoy the local shops and restaurants.
4
War Between the States Museum
Visit the historic site.
Tags
Myrtle Beach to Florence drive
travel to Florence
US-76
driving distance to Florence
best way to Florence
Florence travel guide
SC travel
