Is there a train to Sioux Falls?

No, there is no passenger rail service to Sioux Falls.

Is Sioux Falls walkable?

No, it is a car-dependent city.

How long is the drive?

The drive takes approximately 4 hours.

What is the best airport?

Sioux Falls Regional Airport (FSD) is the primary gateway.

Sioux Falls is a very affordable city for lodging and dining.

Des Moines

Sioux Falls

Driving

Des Moines to Sioux Falls

Updated: 28 May 2026

The distance from Des Moines to Sioux Falls is approximately 450 kilometers. Driving is the most practical mode of travel, taking about 4 hours via I-35 North and I-90 West. This is a straightforward drive through the rolling hills of Iowa and the plains of South Dakota. Sioux Falls is the largest city in South Dakota and is famous for its namesake waterfalls.

Total Distance: Driving distance 450 km, straight-line air distance 400 km.

Fastest Way

Driving via I-35 and I-90, taking approximately 4 hours.

Cheapest Way

Driving your own vehicle is the most cost-effective method.

Compare Des Moines to Sioux Falls Routes

Driving

Direct

Duration

4 hours

Avg Price

$50 in fuel

Operator

Personal Vehicle

Route

I-35 N to I-90 W

The drive is very easy and well-maintained.

Travel Tips

Driving
The drive is very straightforward; follow the signs for I-90 West.
Walking
Sioux Falls is a car-dependent city; plan to drive between attractions.
Safety
Stay alert during the drive and take regular breaks.
Dining
Try the local restaurants in the downtown area; they are excellent.
Planning
Use apps like Google Maps to navigate the city's layout.

Safety Tips

Road Safety
Be aware of changing weather conditions, especially during winter.
Emergency
Dial 911 for any emergencies; the city has a robust police presence.
Pedestrian Safety
Follow traffic signals, as Sioux Falls traffic is generally moderate.
Health
Stay hydrated and take breaks, as the drive can be tiring.