Train
Driving
Perryville to Chicago
Updated: 01 Jun 2026
The trip from Perryville to Chicago is a 380-mile journey heading north. You will take I-55 North the entire way, passing through St. Louis and Springfield, Illinois. The drive takes approximately 6 hours. Alternatively, you can drive to St. Louis and take the Amtrak Lincoln Service train to Chicago.
Total Distance: 610 km driving distance; 530 km straight-line air distance.
Fastest Way
Driving is the fastest, taking 6 hours compared to the train's 8+ hours.
Cheapest Way
Driving is generally cheaper if traveling with more than one person.
Compare Perryville to Chicago Routes
|
Connecting
|
Direct
|
|
|---|---|---|
| Duration | 8 hours | 6 hours |
| Avg Price | $50-$120 | $70-$90 in fuel |
| Operator | Amtrak | Personal Vehicle |
| Route | Drive to St. Louis, then take the Lincoln Service to Union Station. | I-55 North through St. Louis and Springfield, IL. |
| Tip | Book tickets in advance for the best fares. | Avoid entering Chicago during morning or evening rush hours. |
Travel Tips
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ParkingUse apps like SpotHero to find affordable parking in downtown Chicago.
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Public TransitUse the 'L' train system to get around the city efficiently.
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TrafficI-55 traffic near Joliet can be heavy; check maps before leaving.
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DiningTry deep-dish pizza at Lou Malnati's or Giordano's.
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WeatherChicago is windy; pack layers regardless of the season.
Safety Tips
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City AwarenessStay in well-lit, populated areas when walking at night.
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DrivingChicago drivers are aggressive; stay alert and follow lane markings.
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TheftNever leave valuables visible in your car, especially in parking garages.
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EmergencyDial 911 for any emergencies; the city has a rapid response system.
People Also Ask
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Is there a direct train?No, you must drive to St. Louis to catch the Amtrak train.
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How long is the drive?It takes about 6 hours.
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What is the best route?I-55 North is the most direct highway.
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Are there tolls?Yes, expect tolls on the final approach to Chicago.
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Is it better to fly?Driving is usually faster than flying when accounting for airport security.
Quick Info
- From Perryville, Missouri, United States
- To Chicago, Illinois, United States
-
Modes
Best Time to Travel
Summer for festivals or late spring for pleasant city walking weather.
Things to Do in Chicago
1
Millennium Park
See the famous Cloud Gate sculpture, also known as The Bean.
2
Art Institute of Chicago
Explore one of the oldest and largest art museums in the country.
3
Navy Pier
Enjoy rides, restaurants, and lakefront views on this historic pier.
4
Willis Tower
Step onto the Skydeck for incredible views of the city skyline.
Tags
Perryville to Chicago
I-55 North
driving to Chicago
Amtrak to Chicago
Perryville travel
fastest way to Chicago
Illinois road trip
Chicago tourism
