Perryville
Perryville
Springfield
Springfield
Driving

Perryville to Springfield

Updated: 01 Jun 2026

The route from Perryville to Springfield, Missouri, covers approximately 230 miles. You will primarily travel west using US-60, which offers a scenic drive through the Missouri Ozarks. The journey takes about 4 hours. This route is less congested than the interstate highways and provides a more relaxed driving experience.

Total Distance: 370 km driving distance; 330 km straight-line air distance.
Fastest Way
Driving via US-60 is the fastest, taking 4 hours.
Cheapest Way
Driving your own vehicle is the most affordable option.
Compare Perryville to Springfield Routes
Driving
Direct
Duration
4 hours
Avg Price
$40-$55 in fuel
Operator
Personal Vehicle
Route
US-60 West through Poplar Bluff and Willow Springs.

US-60 has many sections with lower speed limits through small towns.

Travel Tips
  • Speed Limits
    Watch for sudden speed limit drops when entering small towns on US-60.
  • Scenic Stops
    Stop in Poplar Bluff for a quick coffee break.
  • Road Quality
    US-60 is well-maintained but watch for deer at dusk.
  • Navigation
    GPS is reliable here, but keep a paper map for backup.
  • Dining
    Try local Ozark-style comfort food in the smaller towns along the way.
Safety Tips
  • Wildlife
    Be extremely cautious of deer crossing the road, especially at night.
  • Passing
    US-60 has many two-lane sections; only pass in designated areas.
  • Weather
    Ozark roads can be winding; drive slowly during rain.
  • Emergency
    Cell service can be intermittent in the deeper parts of the Ozarks.
People Also Ask
  • Is there a train?
    No, there is no passenger rail service to Springfield.
  • How long is the drive?
    The drive takes about 4 hours.
  • What is the best route?
    US-60 West is the most direct path.
  • Are there tolls?
    No, this route is entirely toll-free.
  • Is it a scenic drive?
    Yes, it passes through the beautiful Ozark hills.
Quick Info
  • From Perryville, Missouri, United States
  • To Springfield, Missouri, United States
  • Modes
Best Time to Travel

Autumn is ideal for viewing the fall foliage in the Ozark mountains.

Things to Do in Springfield
1
Bass Pro Shops
Visit the granddaddy of all outdoor stores, featuring massive aquariums.
2
Fantastic Caverns
Take a ride-through tour of these beautiful underground limestone caves.
3
Route 66 Car Museum
See a collection of classic cars along the historic Mother Road.
4
Dickerson Park Zoo
Enjoy a family-friendly day at this well-maintained local zoo.
Tags
Perryville to Springfield MO US-60 route driving to Springfield Missouri Ozarks road trip Perryville travel fastest way to Springfield Missouri travel guide Springfield MO tourism