The drive from Perryville to New Orleans is approximately 650 miles. You will head south on I-55, passing through Memphis and Jackson before reaching the Gulf Coast. The journey takes about 10 hours. This route is a straight shot down the Mississippi River valley.
Total Distance: 1050 km driving distance; 880 km straight-line air distance.
I-55 is a major trucking route; expect heavy traffic.
Spring for Mardi Gras or autumn for cooler weather.