Perryville
Perryville
New Orleans
New Orleans
Driving

Perryville to New Orleans

Updated: 01 Jun 2026

The drive from Perryville to New Orleans is approximately 650 miles. You will head south on I-55, passing through Memphis and Jackson before reaching the Gulf Coast. The journey takes about 10 hours. This route is a straight shot down the Mississippi River valley.

Total Distance: 1050 km driving distance; 880 km straight-line air distance.
Fastest Way
Driving via I-55 is the fastest, taking 10 hours.
Cheapest Way
Driving your own vehicle is the most cost-effective method.
Compare Perryville to New Orleans Routes
Driving
Direct
Duration
10 hours
Avg Price
$110-$140 in fuel
Operator
Personal Vehicle
Route
I-55 South through Memphis and Jackson to New Orleans.

I-55 is a major trucking route; expect heavy traffic.

Travel Tips
  • Traffic
    Expect heavy traffic when entering New Orleans.
  • Dining
    Try authentic gumbo or beignets at Cafe Du Monde.
  • Navigation
    Use GPS to navigate the city's unique street layout.
  • Parking
    Use public parking garages; street parking is difficult.
  • Timing
    Avoid visiting during peak hurricane season if possible.
Safety Tips
  • Driving
    Stay alert on the long stretches of I-55.
  • Weather
    Be aware of potential flooding during heavy rain.
  • Vehicle
    Check your tire pressure before the long drive.
  • Emergency
    Keep a roadside emergency kit in your vehicle.
People Also Ask
  • Is there a train?
    No, there is no passenger rail service to New Orleans.
  • How long is the drive?
    It takes about 10 hours.
  • What is the best route?
    I-55 South is the most direct highway.
  • Are there tolls?
    No, this route is toll-free.
  • Is it a safe drive?
    Yes, it is a standard interstate route.
Quick Info
  • From Perryville, Missouri, United States
  • To New Orleans, Louisiana, United States
  • Modes
Best Time to Travel

Spring for Mardi Gras or autumn for cooler weather.

Things to Do in New Orleans
1
French Quarter
Explore the historic heart of the city with its unique architecture.
2
Garden District
Walk through the beautiful historic homes and gardens.
3
National WWII Museum
Visit this world-class museum dedicated to the war.
4
Bourbon Street
Experience the famous nightlife and music scene.
Tags
Perryville to New Orleans I-55 route driving to New Orleans Perryville travel fastest way to New Orleans Louisiana road trip New Orleans tourism Missouri to Louisiana