Driving
Perryville to Cleveland
Updated: 01 Jun 2026
The drive from Perryville to Cleveland is approximately 650 miles. You will primarily follow I-70 and I-71 North, taking about 10 hours. This is a straightforward drive across the Midwest. Flying is possible but often requires a connection, making driving a very competitive option for this distance.
Total Distance: 1,050 km driving distance and 900 km air distance.
Fastest Way
Driving takes 10 hours.
Cheapest Way
Driving is the most economical and direct way.
Compare Perryville to Cleveland Routes
Driving
Direct
Duration
10 hours
Avg Price
130-190 dollars
Operator
Personal Vehicle
Route
I-55 North to I-70 East, then I-71 North.
Expect heavy traffic in Columbus.
Travel Tips
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DiningTry the local food scene in the Ohio City neighborhood.
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ParkingParking is available in downtown garages.
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WalkingThe city center is walkable, but a car is helpful for suburbs.
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WeatherWinters can be cold and snowy; prepare accordingly.
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EventsCheck for local festivals and events in the city.
Safety Tips
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AwarenessStay alert in urban areas at night.
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DrivingBe cautious of construction zones on I-71.
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EmergencyDial 911 for any emergency needs.
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NavigationUse GPS to navigate the city's highway loop.
People Also Ask
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Is Cleveland safe?Cleveland is generally safe, but exercise standard urban precautions.
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What is the best airport?Cleveland Hopkins International Airport (CLE) is the main hub.
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How long is the drive?It is about 10 hours of driving time.
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Are there tolls?I-71 is mostly toll-free in this region.
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Is the food good?Cleveland has a vibrant and growing food scene.
Quick Info
- From Perryville, Missouri, United States
- To Cleveland, Ohio, United States
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Modes
Best Time to Travel
Summer for pleasant weather and outdoor activities.
Things to Do in Cleveland
1
Rock & Roll Hall of Fame
Explore the history of rock music in this iconic museum.
2
Cleveland Museum of Art
See an extensive collection of art in this world-class museum.
3
West Side Market
Shop at one of the oldest and largest public markets in the U.S.
4
Cleveland Metroparks Zoo
Enjoy this large zoo with a variety of animals.
Tags
Perryville to Cleveland
driving to Cleveland
I-70 and I-71 road trip
traveling to Ohio
Perryville travel
Cleveland trip
Midwest travel
best way to Cleveland
