No, there is no passenger rail service to Denver.

What is the best route?

I-70 is the most direct highway.

Some express lanes in Denver have tolls; check your route.

Yes, it is a standard interstate route.

Perryville

Denver

Driving

Perryville to Denver

Updated: 01 Jun 2026

The drive from Perryville to Denver is approximately 950 miles. You will head west through Missouri, Kansas, and Colorado. The journey takes about 14 hours via I-70. This is a cross-country route connecting the Midwest to the Rocky Mountains.

Total Distance: 1530 km driving distance; 1300 km straight-line air distance.

Fastest Way

Driving via I-70 is the fastest, taking 14 hours.

Cheapest Way

Driving your own vehicle is the most cost-effective method.

Compare Perryville to Denver Routes

Driving

Direct

Duration

14 hours

Avg Price

$160-$190 in fuel

Operator

Personal Vehicle

Route

I-70 West.

Denver traffic is very heavy; plan your arrival accordingly.

Travel Tips

Traffic
Avoid the Denver highway loops during rush hour.
Dining
Try the many international restaurants.
Navigation
Use GPS to navigate the complex highway interchanges in Denver.
Parking
Use public parking garages; street parking is difficult.
Timing
Try to arrive in Denver mid-day to avoid the worst traffic.

Safety Tips

Driving
Stay alert on the long stretches of highway.
Weather
Be aware of potential severe weather in the mountains.
Vehicle
Check your tire pressure before the long drive.
Emergency
Keep a roadside emergency kit in your vehicle.