No, there is no passenger rail service to Phoenix.

What is the best route?

I-40 is the most direct highway.

Some express lanes in Phoenix have tolls; check your route.

Yes, it is a standard interstate route.

Perryville

Phoenix

Driving

Perryville to Phoenix

Updated: 01 Jun 2026

The drive from Perryville to Phoenix is approximately 1,750 miles. You will head west through Oklahoma, Texas, New Mexico, and Arizona. The journey takes about 26 hours via I-40. This is a cross-country route connecting the Midwest to the Southwest.

Total Distance: 2815 km driving distance; 2400 km straight-line air distance.

Fastest Way

Driving via I-40 is the fastest, taking 26 hours.

Cheapest Way

Driving your own vehicle is the most cost-effective method.

Compare Perryville to Phoenix Routes

Driving

Direct

Duration

26 hours

Avg Price

$280-$320 in fuel

Operator

Personal Vehicle

Route

I-55 to I-40 to I-17 South.

Phoenix traffic is very heavy; plan your arrival accordingly.

Travel Tips

Traffic
Avoid the Phoenix highway loops during rush hour.
Dining
Try the many international restaurants.
Navigation
Use GPS to navigate the complex highway interchanges in Phoenix.
Parking
Use public parking garages; street parking is difficult.
Timing
Try to arrive in Phoenix mid-day to avoid the worst traffic.

Safety Tips

Driving
Stay alert on the long stretches of highway.
Weather
Be aware of potential severe weather in the desert.
Vehicle
Check your tire pressure before the long drive.
Emergency
Keep a roadside emergency kit in your vehicle.