No, there is no passenger rail service to Tampa.

What is the best route?

I-75 is the most direct highway.

Some express lanes in Tampa have tolls; check your route.

Yes, it is a standard interstate route.

Perryville

Tampa

Driving

Perryville to Tampa

Updated: 01 Jun 2026

The drive from Perryville to Tampa is approximately 1,050 miles. You will head southeast through Tennessee, Georgia, and Florida. The journey takes about 16 hours via I-75. This is a popular route for those traveling to the Gulf Coast of Florida.

Total Distance: 1690 km driving distance; 1400 km straight-line air distance.

Fastest Way

Driving via I-75 is the fastest, taking 16 hours.

Cheapest Way

Driving your own vehicle is the most cost-effective method.

Compare Perryville to Tampa Routes

Driving

Direct

Duration

16 hours

Avg Price

$180-$210 in fuel

Operator

Personal Vehicle

Route

I-24 to I-75 South.

Tampa traffic is very heavy; plan your arrival accordingly.

Travel Tips

Traffic
Avoid the Tampa highway loops during rush hour.
Dining
Try authentic Cuban cuisine.
Navigation
Use GPS to navigate the complex highway interchanges in Tampa.
Parking
Use public parking garages; street parking is difficult.
Timing
Try to arrive in Tampa mid-day to avoid the worst traffic.

Safety Tips

Driving
Stay alert on the long stretches of highway.
Weather
Be aware of potential severe weather in Florida.
Vehicle
Check your tire pressure before the long drive.
Emergency
Keep a roadside emergency kit in your vehicle.