Perryville
Perryville
Washington
Washington
Flight Driving

Perryville to Washington

Updated: 01 Jun 2026

Traveling from Perryville to Washington, D.C. covers roughly 950 miles. The most direct driving route follows I-64 East through Louisville and Lexington, eventually connecting to I-81 and I-66. This drive takes about 15 hours. Alternatively, you can fly from St. Louis Lambert International Airport to Reagan National Airport. This journey takes you from the Mississippi River valley to the historic Potomac River region.

Total Distance: 1,530 km driving distance and 1,300 km air distance.
Fastest Way
Flying from St. Louis takes 4 hours total travel time.
Cheapest Way
Driving is the most cost-effective for multiple passengers.
Compare Perryville to Washington Routes
Flight
Connecting
Driving
Direct
Duration 4 hours 15 hours
Avg Price 200-500 dollars 200-350 dollars
Operator American Airlines Personal Vehicle
Route STL to DCA via Charlotte or Chicago. I-55 North to I-64 East, then I-81 North to I-66 East.
Tip Reagan National is the most convenient airport for downtown D.C. Expect heavy traffic when entering the D.C. beltway during rush hour.
Travel Tips
  • Metro Usage
    Use the D.C. Metro system to navigate the city; it is faster than driving.
  • Parking
    Parking in D.C. is expensive and scarce; use hotel parking or public transit.
  • Walking
    Wear comfortable shoes as you will likely walk several miles per day.
  • Security
    Expect security screenings at all major government buildings and museums.
  • Dining
    Try the local Ethiopian cuisine, which is highly regarded in the D.C. area.
Safety Tips
  • Awareness
    Stay alert in crowded tourist areas to avoid pickpockets.
  • Night Travel
    Stick to well-lit, populated areas when walking at night.
  • Traffic
    D.C. traffic is notoriously difficult; avoid driving during peak hours.
  • Emergency
    Keep the number for local emergency services saved in your phone.
People Also Ask
  • Is the Metro easy to use?
    Yes, the Metro is very intuitive with color-coded lines.
  • Are museums free?
    Most Smithsonian museums in D.C. are free to the public.
  • What is the best time to visit?
    Spring and Fall offer the most comfortable weather.
  • Can I drive to the Capitol?
    Driving to the Capitol is possible, but parking is extremely limited.
  • How far is the drive?
    It is approximately 950 miles or 15 hours of driving.
Quick Info
  • From Perryville, Missouri, United States
  • To Washington, District of Columbia, United States
  • Modes
Best Time to Travel

April for the Cherry Blossom Festival or October for pleasant autumn weather.

Things to Do in Washington
1
National Mall
Walk the length of the Mall to see the Lincoln Memorial and Washington Monument. It is the heart of the city.
2
Smithsonian Museums
Visit the Air and Space Museum or the Museum of Natural History. Admission is free for all.
3
Georgetown
Explore the historic streets and waterfront of Georgetown. It offers great dining and shopping.
4
U.S. Capitol
Take a guided tour of the Capitol building. Book your tickets in advance online.
Tags
Perryville to Washington DC driving to DC from Missouri flights from STL to DCA I-64 road trip traveling to Washington DC Perryville travel DC trip planning Midwest to East Coast travel